Development of non-invasive flexible directional microwave ablation for central lung cancer: a simulation study.
Phys Med Biol
; 69(9)2024 Apr 22.
Article
em En
| MEDLINE
| ID: mdl-38527368
ABSTRACT
Transbronchial microwave ablation (MWA) with flexible antennas has gradually become an attractive alternative to percutaneous MWA for lung cancer due to its characteristic of non-invasiveness. However, flexible antennas for the precision ablation of lung tumors that are adjacent to critical bronchial structures are still not available. In this study, a non-invasive flexible directional (FD) antenna for early stage central lung tumors surrounding the bronchia was proposed. A comprehensive numerical MWA model with the FD antenna was developed in a real human-sized left lung model. The structure of the antenna and the treatment protocol were optimized by a generic algorithm for the precision ablation of two cases of early stage central lung cancer (i.e. spherical-like and ellipsoidal tumors). The electromagnetic efficiency of the optimized antenna was also improved by implementing an optimizedπ-matching network for impedance matching. The results indicate that the electromagnetic energy of MWA can be restricted to a particular area for precision ablation of specific lung tumors using the FD antenna. This study contributes to the field of lung cancer management with MWA.
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Base de dados:
MEDLINE
Assunto principal:
Técnicas de Ablação
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Neoplasias Pulmonares
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Micro-Ondas
Limite:
Humans
Idioma:
En
Revista:
Phys Med Biol
Ano de publicação:
2024
Tipo de documento:
Article