Mycobacterial spindle cell pseudotumor of the spinal cord: Case report and literature review.
J Neuroimmunol
; 390: 578329, 2024 05 15.
Article
em En
| MEDLINE
| ID: mdl-38554665
ABSTRACT
We report the first description of spinal cord mycobacterial spindle cell pseudotumor. A patient with newly diagnosed advanced HIV presented with recent-onset bilateral leg weakness and was found to have a hypermetabolic spinal cord mass on structural and molecular imaging. Biopsy and cultures from blood and cerebrospinal fluid confirmed spindle cell pseudotumor due to Mycobacterium avium-intracellulare. Despite control of HIV and initial reduction in pseudotumor volume on antiretrovirals and antimycobacterials (azithromycin, ethambutol, rifampin/rifabutin), he ultimately experienced progressive leg weakness due to pseudotumor re-expansion. Here, we review literature and discuss multidisciplinary diagnosis, monitoring and management challenges, including immune reconstitution inflammatory syndrome.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infecção por Mycobacterium avium-intracellulare
Limite:
Adult
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Humans
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Male
Idioma:
En
Revista:
J Neuroimmunol
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J. neuroimmunol
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Journal of neuroimmunology
Ano de publicação:
2024
Tipo de documento:
Article