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Microbial composition associated with biliary stents in patients undergoing pancreatic resection for cancer.
Blanco-Míguez, Aitor; Carloni, Sara; Cardenas, Cindy; Dioguardi, Carola Conca; Lambroia, Luca; Capretti, Giovanni; Nappo, Gennaro; Fugazza, Alessandro; Capogreco, Antonio; Armanini, Federica; Asnicar, Francesco; Dubois, Leonard; Golzato, Davide; Manghi, Paolo; Pinto, Federica; Scuderi, Cristina; Casari, Erminia; Montorsi, Marco; Anderloni, Andrea; Rescigno, Maria; Repici, Alessandro; Zerbi, Alessandro; Peano, Clelia; Tamburini, Sabrina; Rusconi, Roberto; Segata, Nicola.
Afiliação
  • Blanco-Míguez A; Department CIBIO, University of Trento, Trento, Italy.
  • Carloni S; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.
  • Cardenas C; IRCCS Humanitas Research Hospital, Rozzano, Italy.
  • Dioguardi CC; Institute of Genetics and Biomedical Research, UoS of Milan, National Research Council, Rozzano, Milan, Italy.
  • Lambroia L; Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
  • Capretti G; Department of Pancreatic Surgery, IRCCS Humanitas Research Hospital, Rozzano, Italy.
  • Nappo G; Department of Pancreatic Surgery, IRCCS Humanitas Research Hospital, Rozzano, Italy.
  • Fugazza A; Department of Gastroenterology, IRCCS Humanitas Research Hospital, Rozzano, Italy.
  • Capogreco A; Department of Gastroenterology, IRCCS Humanitas Research Hospital, Rozzano, Italy.
  • Armanini F; Department CIBIO, University of Trento, Trento, Italy.
  • Asnicar F; Department CIBIO, University of Trento, Trento, Italy.
  • Dubois L; Department CIBIO, University of Trento, Trento, Italy.
  • Golzato D; Department CIBIO, University of Trento, Trento, Italy.
  • Manghi P; Department CIBIO, University of Trento, Trento, Italy.
  • Pinto F; Department CIBIO, University of Trento, Trento, Italy.
  • Scuderi C; Microbiology and Virology Unit, IRCCS Humanitas Research Hospital, Rozzano, Italy.
  • Casari E; Microbiology and Virology Unit, IRCCS Humanitas Research Hospital, Rozzano, Italy.
  • Montorsi M; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.
  • Anderloni A; Department of Gastroenterology, IRCCS Humanitas Research Hospital, Rozzano, Italy.
  • Rescigno M; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.
  • Repici A; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.
  • Zerbi A; Department of Gastroenterology, IRCCS Humanitas Research Hospital, Rozzano, Italy.
  • Peano C; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.
  • Tamburini S; Department of Pancreatic Surgery, IRCCS Humanitas Research Hospital, Rozzano, Italy.
  • Rusconi R; Institute of Genetics and Biomedical Research, UoS of Milan, National Research Council, Rozzano, Milan, Italy.
  • Segata N; Human Technopole, Milan, Italy.
NPJ Biofilms Microbiomes ; 10(1): 35, 2024 Mar 30.
Article em En | MEDLINE | ID: mdl-38555334
ABSTRACT
Malignant bile duct obstruction is typically treated by biliary stenting, which however increases the risk of bacterial infections. Here, we analyzed the microbial content of the biliary stents from 56 patients finding widespread microbial colonization. Seventeen of 36 prevalent stent species are common oral microbiome members, associate with disease conditions when present in the gut, and include dozens of biofilm- and antimicrobial resistance-related genes. This work provides an overview of the microbial communities populating the stents.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções Bacterianas / Colestase / Neoplasias Limite: Humans Idioma: En Revista: NPJ Biofilms Microbiomes Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Itália

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções Bacterianas / Colestase / Neoplasias Limite: Humans Idioma: En Revista: NPJ Biofilms Microbiomes Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Itália