Surviving in a multistressor world: Gene expression changes in earthworms exposed to heat, desiccation, and chemicals.
Environ Toxicol Pharmacol
; 108: 104428, 2024 Jun.
Article
em En
| MEDLINE
| ID: mdl-38570150
ABSTRACT
An investigation of the effects of anthropogenic stress on terrestrial ecosystems is urgently needed. In this work, we explored how exposure to heat, desiccation, and chemical stress alters the expression of genes that encode heat shock proteins (HSPs), an enzyme that responds to oxidative stress (CAT), hypoxia-related proteins (HIF1 and HYOU), and a DNA repair-related protein (PARP1) in the earthworm Eisenia fetida. Exposure to heat (31°C) for 24â¯h upregulated HSPs and hypoxia-related genes, suggesting possible acquired thermotolerance. Desiccation showed a similar expression profile; however, the HSP response was activated to a lesser extent. Heat and desiccation activated the small HSP at 24â¯h, suggesting that they may play a role in adaptation. Simultaneous exposure to endosulfan and temperature for 7â¯h upregulated all of the evaluated genes, implicating a coordinated response involving multiple biological processes to ensure survival and acclimation. These results highlight the relevance of multistress analysis in terrestrial invertebrates.
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Base de dados:
MEDLINE
Assunto principal:
Oligoquetos
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Temperatura Alta
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Proteínas de Choque Térmico
Limite:
Animals
Idioma:
En
Revista:
Environ Toxicol Pharmacol
Ano de publicação:
2024
Tipo de documento:
Article