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An IL-1ß-driven neutrophil-stromal cell axis fosters a BAFF-rich protumor microenvironment in individuals with multiple myeloma.
de Jong, Madelon M E; Fokkema, Cathelijne; Papazian, Natalie; Czeti, Ágnes; Appelman, Marjolein K; Vermeulen, Michael; van Heusden, Teddie; Hoogenboezem, Remco M; van Beek, Gregory; Tahri, Sabrin; Sanders, Mathijs A; van de Woestijne, Pieter C; Gay, Francesca; Moreau, Philippe; Büttner-Herold, Maike; Bruns, Heiko; van Duin, Mark; Broijl, Annemiek; Sonneveld, Pieter; Cupedo, Tom.
Afiliação
  • de Jong MME; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.
  • Fokkema C; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.
  • Papazian N; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.
  • Czeti Á; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.
  • Appelman MK; Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary.
  • Vermeulen M; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.
  • van Heusden T; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.
  • Hoogenboezem RM; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.
  • van Beek G; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.
  • Tahri S; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.
  • Sanders MA; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.
  • van de Woestijne PC; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.
  • Gay F; Department of Cardiothoracic Surgery, Erasmus Medical Center, Rotterdam, the Netherlands.
  • Moreau P; Clinical Trial Unit, Division of Hematology, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, University of Torino, Torino, Italy.
  • Büttner-Herold M; Department of Hematology, Nantes University Hospital Hotel-Dieu, Nantes, France.
  • Bruns H; Department of Internal Medicine 5, Hematology and Oncology, Friedrich Alexander University Erlangen-Nuremberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.
  • van Duin M; Department of Internal Medicine 5, Hematology and Oncology, Friedrich Alexander University Erlangen-Nuremberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.
  • Broijl A; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.
  • Sonneveld P; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.
  • Cupedo T; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands. p.sonneveld@erasmusmc.nl.
Nat Immunol ; 25(5): 820-833, 2024 May.
Article em En | MEDLINE | ID: mdl-38600356
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Estromais / Interleucina-1beta / Fator Ativador de Células B / Microambiente Tumoral / Mieloma Múltiplo / Neutrófilos Limite: Humans Idioma: En Revista: Nat Immunol Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Holanda
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Estromais / Interleucina-1beta / Fator Ativador de Células B / Microambiente Tumoral / Mieloma Múltiplo / Neutrófilos Limite: Humans Idioma: En Revista: Nat Immunol Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Holanda