Potential for targeting small heat shock protein modifications.
Trends Pharmacol Sci
; 45(7): 583-585, 2024 Jul.
Article
em En
| MEDLINE
| ID: mdl-38704305
ABSTRACT
Small heat shock proteins (sHSPs) play key roles in cellular stress and several human diseases. The direct effects of some post-translational modifications (PTMs) on certain sHSPs have been characterized, raising the possibility that small molecules could be used to modulate these modifications and indirectly up- or downregulate sHSP activity.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Processamento de Proteína Pós-Traducional
/
Proteínas de Choque Térmico Pequenas
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Trends Pharmacol Sci
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Estados Unidos