Diffuse infiltrating tumour with the molecular profile of an atypical teratoid rhabdoid tumour (AT/RT SHH-1B) in an adult patient.

Cordier, Fleur; Schouten, Joost W; Geurts, Marjolein; Kros, Johan M; Dubbink, Hendrikus J; Verlinden, Vincent; Federico, Aniello; Kool, Marcel; Maas, Sybren L N

Cordier, Fleur; Schouten, Joost W; Geurts, Marjolein; Kros, Johan M; Dubbink, Hendrikus J; Verlinden, Vincent; Federico, Aniello; Kool, Marcel; Maas, Sybren L N.

Afiliação

Cordier F; Department of Pathology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Schouten JW; Department of Pathology, University Hospital Ghent, Ghent, Belgium.
Geurts M; Department of Neurosurgery, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Kros JM; Department of Neurology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Dubbink HJ; Department of Pathology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Verlinden V; Department of Pathology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Federico A; Department of Radiology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Kool M; Hopp Childrens Cancer Center (KiTZ), Heidelberg, Germany.
Maas SLN; German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.

Neuropathol Appl Neurobiol ; 50(3): e12983, 2024 Jun.

Article em En | MEDLINE | ID: mdl-38708554

ABSTRACT

ABSTRACT

We describe a 46-year-old patient with an IDH-wildtype diffusely infiltrating atypical teratoid/rhabdoid tumour (AT/RT), SHH-1B molecular subtype. The unusual histology and subsequent diagnosis in an adult patient will be discussed.

Assuntos

Neoplasias Encefálicas; Tumor Rabdoide; Teratoma; Humanos; Tumor Rabdoide/patologia; Tumor Rabdoide/genética; Teratoma/patologia; Teratoma/genética; Pessoa de Meia-Idade; Neoplasias Encefálicas/patologia; Neoplasias Encefálicas/genética; Masculino; Proteínas Hedgehog/genética

Palavras-chave

atypical teratoid/rhabdoid tumour; methylation sequencing; molecular techniques; neurooncology

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Teratoma / Neoplasias Encefálicas / Tumor Rabdoide Limite: Humans / Male / Middle aged Idioma: En Revista: Neuropathol Appl Neurobiol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Holanda

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google