Factors influencing gastrostomy tube feeding duration and nutrition outcomes in pediatric patients with Down syndrome: A descriptive cohort study.
JPEN J Parenter Enteral Nutr
; 48(5): 605-613, 2024 Jul.
Article
em En
| MEDLINE
| ID: mdl-38715451
ABSTRACT
BACKGROUND:
Feeding difficulty is widely recognized in patients with Down syndrome, and many patients require gastrostomy tube (G-tube) placement for nutrition. No reliable factors have been identified to predict the expected duration of G-tube feeds in patients with Down syndrome. This descriptive cohort study aimed to determine the factors affecting the duration of G-tube feeds. We also investigated change in body mass index (BMI) from G-tube placement to discontinuation.METHODS:
Medical records of patients with Down syndrome seen by a pediatric gastroenterologist at a tertiary care center between September 1986 and December 2021 were reviewed. Data collection included demographics, anthropometrics, comorbidities, and feeding route. Comparison was performed between patients who discontinued G-tube feeds and those who did not.RESULTS:
Two hundred twenty patients (45% female) were included. The median age at G-tube placement was 5 months (interquartile range [IQR] 0.2-1.3 years). There were 113 (51%) patients who discontinued G-tube feeds, after a median duration of 31.6 months (IQR 15.6-55.7 months). Tracheostomy was the only covariant associated with a longer duration of G-tube feeds (158 months vs 53 months; P = 0.002). Neither age at G-tube placement nor any comorbidities were associated with BMI status at discontinuation of G-tube.CONCLUSION:
In our cohort of patients with Down syndrome, age at placement of G-tube did not impact the duration of G-tube feeds. Most patients who had a G-tube placed were likely to require enteral feeds for at least 1 year. Those who had a tracheostomy needed their G-tube for a longer time.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Gastrostomia
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Nutrição Enteral
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Síndrome de Down
Limite:
Child, preschool
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Female
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Humans
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Infant
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Male
Idioma:
En
Revista:
JPEN J Parenter Enteral Nutr
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Estados Unidos