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Novel insights into the management of rheumatoid arthritis: one year in review 2024.
Molteni, Emanuele; Adinolfi, Antonella; Bondi, Valentina; Delvino, Paolo; Sakellariou, Garifallia; Trentanni, Carlo; Ughi, Nicola; Pozzi, Maria Rosa; Scirè, Carlo Alberto.
Afiliação
  • Molteni E; Rheumatology Unit, IRCCS San Gerardo dei Tintori, Monza, Italy.
  • Adinolfi A; Rheumatology Division, Multispecialist Medical Department, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
  • Bondi V; Rheumatology, School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
  • Delvino P; Rheumatology Unit, IRCCS San Gerardo dei Tintori, Monza, and Rheumatology, School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
  • Sakellariou G; Department of Internal Medicine and Medical Therapy, University of Pavia, and Istituti Clinici Scientifici Maugeri IRCCS Pavia, Italy.
  • Trentanni C; Rheumatology, School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
  • Ughi N; Rheumatology Division, Multispecialist Medical Department, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
  • Pozzi MR; Rheumatology Unit, IRCCS San Gerardo dei Tintori, Monza, Italy.
  • Scirè CA; Rheumatology Unit, IRCCS San Gerardo dei Tintori, Monza; Rheumatology, School of Medicine and Surgery, University of Milano-Bicocca, Milan, and Epidemiology Unit, Italian Society for Rheumatology, Milan, Italy. carlo.scire@unimib.it.
Clin Exp Rheumatol ; 42(5): 947-960, 2024 May.
Article em En | MEDLINE | ID: mdl-38743447
ABSTRACT
New evidence from 2023 has slightly shifted some perspectives on rheumatoid arthritis (RA) management. Glucocorticoids have reaffirmed their role as bridging therapy, while novel studies on JAK inhibitors have examined efficacy, mechanism of action, and their potential in high-risk populations, bolstering our understanding with real-world data.Additionally, among treatment strategies, achieving low disease activity has emerged as comparable to achieving remission in the long term, and new insights have been gained regarding tapering both biological and conventional synthetic DMARDs. Furthermore, novel approaches have been proposed for managing difficult-to-treat RA and pre-RA. In this paper, the reviewers aim to present the most relevant studies published during the last year in the field of RA management.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Antirreumáticos / Inibidores de Janus Quinases / Glucocorticoides Limite: Humans Idioma: En Revista: Clin Exp Rheumatol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Itália

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Antirreumáticos / Inibidores de Janus Quinases / Glucocorticoides Limite: Humans Idioma: En Revista: Clin Exp Rheumatol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Itália