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Durable response to BRAF inhibitor monotherapy in recurrent metastatic low grade serous ovarian cancer.
Sama, Shashank; Rosqvist, Sterling; Savage, Talicia; Lomo, Lesley; Sibbald, Kiera; Straubhar, Alli; Werner, Theresa L.
Afiliação
  • Sama S; Huntsman Cancer Institute at the University of Utah, Salt Lake City, UT, USA.
  • Rosqvist S; University of Utah, Salt Lake City, UT, USA.
  • Savage T; Huntsman Cancer Institute at the University of Utah, Salt Lake City, UT, USA.
  • Lomo L; Huntsman Cancer Institute at the University of Utah, Salt Lake City, UT, USA.
  • Sibbald K; University of Utah, Salt Lake City, UT, USA.
  • Straubhar A; Intermountain Hospital, USA.
  • Werner TL; Huntsman Cancer Institute at the University of Utah, Salt Lake City, UT, USA.
Gynecol Oncol Rep ; 53: 101412, 2024 Jun.
Article em En | MEDLINE | ID: mdl-38779189
ABSTRACT
Low grade serous ovarian cancers (LGSOC) in an advanced setting have limited systemic treatment options. In this paper we report a case of metastatic LGSOC harboring a BRAF mutation, treated with dabrafenib. We discuss the clinical, pathologic and molecular characteristics as well as surgical considerations and ongoing investigations in LGSOC.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Gynecol Oncol Rep Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Gynecol Oncol Rep Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos