Phylogenomic analyses of multidrug resistant Corynebacterium striatum strains isolated from patients in a tertiary care hospital in the UK.
Eur J Clin Microbiol Infect Dis
; 43(7): 1495-1501, 2024 Jul.
Article
em En
| MEDLINE
| ID: mdl-38801486
ABSTRACT
Corynebacterium striatum is an emerging nosocomial pathogen. This is the first report showing the presence of three distinct multidrug resistant lineages of C. striatum among patients in a UK hospital. The presence of ErmX, Tet(W), Bla and AmpC proteins, and mutations in gyrA gene are associated with the resistance to clindamycin, doxycycline, penicillin and moxifloxacin, respectively. These strains are equipped with several corynebacterial virulence genes including two SpaDEF-type and a novel pilus gene cluster, which needs further molecular characterisation. This study highlights a need of developing an active surveillance strategy for routine monitoring and preventing potential cross-transmission among susceptible patients.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Filogenia
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Corynebacterium
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Infecções por Corynebacterium
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Farmacorresistência Bacteriana Múltipla
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Centros de Atenção Terciária
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Antibacterianos
Limite:
Female
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Humans
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Male
País/Região como assunto:
Europa
Idioma:
En
Revista:
Eur J Clin Microbiol Infect Dis
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Eur. j. clin. microbiol. infect. dis
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European journal of clinical microbiology and infectious diseases
Assunto da revista:
DOENCAS TRANSMISSIVEIS
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MICROBIOLOGIA
Ano de publicação:
2024
Tipo de documento:
Article