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The role of concomitant coronary artery bypass grafting in acute type A aortic dissection complicated by coronary malperfusion.
Pitts, Leonard; Kofler, Markus; Montagner, Matteo; Heck, Roland; Kurz, Stephan Dominik; Sündermann, Simon; Falk, Volkmar; Kempfert, Jörg.
Afiliação
  • Pitts L; Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charité (DHZC), Berlin, Germany.
  • Kofler M; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.
  • Montagner M; Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charité (DHZC), Berlin, Germany.
  • Heck R; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.
  • Kurz SD; DZHK (German Centre for Cardiovascular Research), Berlin, Germany.
  • Sündermann S; Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charité (DHZC), Berlin, Germany.
  • Falk V; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.
  • Kempfert J; Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charité (DHZC), Berlin, Germany.
Eur J Cardiothorac Surg ; 66(1)2024 Jul 01.
Article em En | MEDLINE | ID: mdl-38905500
ABSTRACT

OBJECTIVES:

Managing acute type A aortic dissection with coronary malperfusion is challenging. This study outlines our revascularization strategy for these patients.

METHODS:

Patients undergoing surgery for acute type A aortic dissection with coronary malperfusion and aortic root involvement from January 2000 to December 2021 were included. Patients were classified using the Neri classification for coronary dissection, including a novel 'Neri -' class (no coronary dissection). Patients undergoing revascularization either as a planned or as a bailout strategy due to persisting low cardiac output were compared additionally.

RESULTS:

The cohort comprised 195 patients 43 (22%) Neri -, 43 (22%) Neri A, 74 (38%) Neri B and 35 (18%) Neri C. Aortic root replacement was mainly performed in 25 Neri C patients (71%; P < 0.001). Concomitant bypass surgery was performed in 4 (9%) of Neri -, 5 (12%) of Neri A, 21 (28%) of Neri B and 32 (91%) of Neri C patients (P < 0.001). Thirty-day mortality was 42% with 21 (49%) Neri -, 12 (28%) Neri A, 30 (41%) Neri B and 19 (54%) Neri C patients (P = 0.087). Bailout revascularization was primarily performed in 11 Neri B patients (69%; P = 0.001) and associated with a higher 30-day mortality of 81% compared to 48% for planned revascularization (P = 0.042).

CONCLUSIONS:

Postoperative outcomes in case of coronary malperfusion are poor, irrespective of the anatomic dissection pattern. The decision for concomitant bypass surgery is crucial but may be considered in Neri C patients combined with aortic root replacement. Bailout revascularization was most common in Neri B and showed dismal outcome.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ponte de Artéria Coronária / Dissecção Aórtica Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Cardiothorac Surg Assunto da revista: CARDIOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ponte de Artéria Coronária / Dissecção Aórtica Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Cardiothorac Surg Assunto da revista: CARDIOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Alemanha