Feasibility and effectiveness of extended-release buprenorphine (XR-BUP) among correctional populations: a systematic review.
Am J Drug Alcohol Abuse
; : 1-20, 2024 Jun 28.
Article
em En
| MEDLINE
| ID: mdl-38940929
ABSTRACT
Background:
Medications for opioid use disorder (MOUD) reduce risks for overdose among correctional populations. Among other barriers, daily dosing requirements hinder treatment continuity post-release. Extended-release buprenorphine (XR-BUP) may therefore be beneficial. However, limited evidence exists.Objectives:
To conduct a systematic review examining the feasibility and effectiveness of XR-BUP among correctional populations.Methods:
Searches were carried out in Pubmed, Embase, and PsychINFO in October 2023. Ten studies reporting on feasibility or effectiveness of XR-BUP were included, representing n = 819 total individuals (81.6% male). Data were extracted and narratively reported under the following mainoutcomes:
1) Feasibility; 2) Effectiveness; and 3) Barriers and Facilitators.Results:
Studies were heterogeneous. Correctional populations were two times readier to try XR-BUP compared to non-correctional populations. XR-BUP was feasible and safe, with no diversion, overdoses, or deaths; several negative side effects were reported. Compared to other MOUD, XR-BUP significantly reduced drug use, resulted in similar or higher treatment retention rates, fewer re-incarcerations, and was cost-beneficial, with a lower overall monthly/yearly cost. Barriers to XR-BUP, such as side effects and a fear of needles, as well as facilitators, such as a lowered risk of opioid relapse, were also identified.Conclusion:
XR-BUP appears to be a feasible and potentially effective alternative treatment option for correctional populations with OUD. XR-BUP may reduce community release-related risks, such as opioid use and overdose risk, as well as barriers to treatment retention. Efforts to expand access to and uptake of XR-BUP among correctional populations are warranted.
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Base de dados:
MEDLINE
Idioma:
En
Revista:
Am J Drug Alcohol Abuse
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Canadá