Self-help interventions for the prevention of relapse in mood disorder: a systematic review and meta-analysis.
Fam Pract
; 2024 Jul 17.
Article
em En
| MEDLINE
| ID: mdl-39016242
ABSTRACT
INTRODUCTION:
Self-help interventions may offer a scalable adjunct to traditional care, but their effectiveness in relapse prevention is not well-established.Objectives:
This review aimed to assess their effectiveness in preventing relapses among individuals with mood disorders.METHODS:
We systematically reviewed the pertinent trial literature in Web of Science, EMBASE, PubMed, PsycINFO, and Cochrane databases until May 2024. Randomized controlled trials that examined the self-help interventions among individuals diagnosed with major depressive disorder (MDD) or bipolar disorder (BD) were included. The random-effects model computed the pooled risk ratios of relapse, with subgroup analyses and meta-regression analyses to explore heterogeneity sources.RESULTS:
Fifteen papers and 16 comparisons of randomized trials involving 2735 patients with mood disorders were eligible for this meta-analysis. Adjunct self-help interventions had a small but significant effect on reducing the relapse rates of major depressive disorder (pooled risk ratio 0.78, 95% confidence interval (CI) 0.66-0.92, Pâ =â 0.0032, NNTâ =â 11), and were marginally better in bipolar disorder (pooled risk ratio 0.62, 95% CI 0.40-0.97, Pâ =â .0344, NNTâ =â 12), as compared to treatment as usual (TAU). No subgroup difference was found based on intervention components, settings, delivery method, or guidance levels. The average dropout rate for self-help interventions (18.9%) did not significantly differ from TAU dropout rates. The examination of treatment adherence was highly variable, precluding definitive conclusions.CONCLUSIONS:
Self-help interventions demonstrate a modest preventative effect on relapse in mood disorders, despite low to very low certainty. Future research is essential to identify which elements of self-help interventions are most effective.
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Base de dados:
MEDLINE
Idioma:
En
Revista:
Fam Pract
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Hong Kong