Rationalizing Diverse Binding Mechanisms to the Same Protein Fold: Insights for Ligand Recognition and Biosensor Design.

Leonard, Alison C; Friedman, Anika J; Chayer, Rachel; Petersen, Brian M; Woojuh, Janty; Xing, Zenan; Cutler, Sean R; Kaar, Joel L; Shirts, Michael R; Whitehead, Timothy A

Leonard, Alison C; Friedman, Anika J; Chayer, Rachel; Petersen, Brian M; Woojuh, Janty; Xing, Zenan; Cutler, Sean R; Kaar, Joel L; Shirts, Michael R; Whitehead, Timothy A.

Afiliação

Leonard AC; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, Colorado 80305, United States.
Friedman AJ; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, Colorado 80305, United States.
Chayer R; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, Colorado 80305, United States.
Petersen BM; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, Colorado 80305, United States.
Woojuh J; Department of Botany and Plant Sciences, University of California, Riverside, California 92521-9800, United States.
Xing Z; Institute for Integrative Genome Biology, University of California, Riverside, Riverside, California 92521, United States.
Cutler SR; Center for Plant Cell Biology, University of California, Riverside, Riverside, California 92521, United States.
Kaar JL; Department of Botany and Plant Sciences, University of California, Riverside, California 92521-9800, United States.
Shirts MR; Institute for Integrative Genome Biology, University of California, Riverside, Riverside, California 92521, United States.
Whitehead TA; Center for Plant Cell Biology, University of California, Riverside, Riverside, California 92521, United States.

ACS Chem Biol ; 19(8): 1757-1772, 2024 Aug 16.

Article em En | MEDLINE | ID: mdl-39017707

Assuntos

Técnicas Biossensoriais; Simulação de Dinâmica Molecular; Ligação Proteica; Técnicas Biossensoriais/métodos; Ligantes; Morfolinas/química; Morfolinas/metabolismo; Benzoxazinas/química; Benzoxazinas/metabolismo; Naftalenos/química; Naftalenos/metabolismo; Dobramento de Proteína; Engenharia de Proteínas; Proteínas de Arabidopsis/metabolismo; Proteínas de Arabidopsis/química

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ligação Proteica / Técnicas Biossensoriais / Simulação de Dinâmica Molecular Idioma: En Revista: ACS Chem Biol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google