Protective alleles and precision healthcare in crewed spaceflight.
Nat Commun
; 15(1): 6158, 2024 Jul 22.
Article
em En
| MEDLINE
| ID: mdl-39039045
ABSTRACT
Common and rare alleles are now being annotated across millions of human genomes, and omics technologies are increasingly being used to develop health and treatment recommendations. However, these alleles have not yet been systematically characterized relative to aerospace medicine. Here, we review published alleles naturally found in human cohorts that have a likely protective effect, which is linked to decreased cancer risk and improved bone, muscular, and cardiovascular health. Although some technical and ethical challenges remain, research into these protective mechanisms could translate into improved nutrition, exercise, and health recommendations for crew members during deep space missions.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Voo Espacial
/
Alelos
/
Medicina de Precisão
Limite:
Humans
Idioma:
En
Revista:
Nat Commun
Assunto da revista:
BIOLOGIA
/
CIENCIA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Japão