Epidemiology and genotypic diversity of feline bocavirus identified from cats in Harbin, China.
Virology
; 598: 110188, 2024 Oct.
Article
em En
| MEDLINE
| ID: mdl-39059190
ABSTRACT
Feline bocavirus (FBoV) is a globally distributed linear, single-stranded DNA virus infect cats, currently classified into three distinct genotypes. Although FBoV can lead to systemic infections, its complete pathogenic potential remains unclear. In this study, 289 blood samples were collected from healthy cats in Harbin, revealing an overall FBoV prevalence of 12.1%. Notably, genotypes 1 and 3 of FBoV were found co-circulating among the cat population in Harbin. Additionally, recombination events were detected, particularly in the newly discovered NG/104 and DL/102 strains. Furthermore, negative selection sites were predominantly observed across the protein coding genes of FBoV. These findings suggest a co-circulation of genetically diverse FBoV strains among cats in Harbin, indicate that purifying selection is the primary driving force shaping the genomic evolution of FBoV, and also underscore the importance of comprehensive surveillance efforts to enhance our understanding of the epidemiology and evolutionary characteristics of FBoV.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Filogenia
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Variação Genética
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Doenças do Gato
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Infecções por Parvoviridae
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Bocavirus
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Genótipo
Limite:
Animals
País/Região como assunto:
Asia
Idioma:
En
Revista:
Virology
Ano de publicação:
2024
Tipo de documento:
Article