A model study on the effect of human's height variability in particle deposition and retained dose in the respiratory tract.
Environ Sci Pollut Res Int
; 31(38): 50198-50208, 2024 Aug.
Article
em En
| MEDLINE
| ID: mdl-39090297
ABSTRACT
The objective of the current study was to investigate the impact of human's height variability to the deposition percentage, the deposited and the retained dose of particulate matter in the respiratory tract. In addition, the dose to the oesophagus, blood and lymph nodes was evaluated after particle clearance. A methodology which correlates anatomical and physiological parameters with height was adopted into an existing particle dosimetry model (Exposure Dose Model 2, ExDoM2). Model results showed that deposition of particles with aerodynamic diameter (dae) ranging from 0.001 to 10 µm depends on the competition between anatomical/physiological parameters, with the maximum effect induced from height variability to be observed for particles in the size range of 0.30 µm Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tamanho da Partícula
/
Sistema Respiratório
/
Material Particulado
Limite:
Humans
Idioma:
En
Revista:
Environ Sci Pollut Res Int
/
Environ. sci. pollut. res. int. (Internet)
/
Environmental science and pollution research international (Internet)
Assunto da revista:
SAUDE AMBIENTAL
/
TOXICOLOGIA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Grécia