Pergolide mesylate inhibits exercise-induced prolactin release in man.
Fertil Steril
; 43(4): 628-31, 1985 Apr.
Article
em En
| MEDLINE
| ID: mdl-3987929
ABSTRACT
The effects of Pergolide, a potent dopamine agonist, on exercise-induced plasma prolactin (PRL) changes were studied in normal men. Exercises consisted of a graded bicycle ergometer test and of a 20-km endurance run. In both circumstances, treatment with Pergolide, when compared with placebo or control values, resulted in a significant suppression of basal PRL (P less than 0.001) as well as of exercise-induced PRL increase (P less than 0.01). From these experiments it was concluded that augmented levels of PRL in plasma, as seen during or after muscular exercise, are caused by increased pituitary secretion, rather than decreased elimination.
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Base de dados:
MEDLINE
Assunto principal:
Prolactina
/
Antagonistas de Dopamina
/
Ergolinas
/
Esforço Físico
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Fertil Steril
Ano de publicação:
1985
Tipo de documento:
Article