A morphometric study of the effects of maturation and aging on synaptic patterns in the spinal trigeminal nucleus of the cat.
Brain Res
; 345(1): 25-33, 1985 Oct 14.
Article
em En
| MEDLINE
| ID: mdl-4063803
ABSTRACT
Morphometric methods have been used to study the synaptic and terminal patterns in cat trigeminal nucleus, pars interpolaris, during development and aging. Ages 1, 3, 6, 11, 16, 21, 27, 110, 600 days and 8 and 11 years were studied. Both proportions and densities (number per unit area) of certain terminals and synapses showed significant changes with age. Axoaxonic synapses especially showed two major periods of increase (3-6 days and 21-27 days). The values of most parameters increased in the 21-27 day period to peak levels and then decreased gradually with age. The results indicate two separate critical synaptogenic periods of development and a loss of synaptic elements in aging. Factors contributing to these changes are discussed as is the potential for plasticity in the different afferents at each period.
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Base de dados:
MEDLINE
Assunto principal:
Núcleo Espinal do Trigêmeo
Limite:
Animals
Idioma:
En
Revista:
Brain Res
Ano de publicação:
1985
Tipo de documento:
Article