Homogenous rabbit 7S anti-IgG with antibody specificity for peptidoglycan.
J Exp Med
; 138(5): 1184-93, 1973 Nov 01.
Article
em En
| MEDLINE
| ID: mdl-4126769
ABSTRACT
The relationship between 7S anti-IgG and antibodies to streptococcal cell wall peptidoglycan was examined for four streptococcal Group C antisera. Homogeneous 7S anti-IgG components in these sera were isolated by means of an IgG immunoadsorbent column. For two of the four antisera, the anti-peptidoglycan activity of the 7S anti-IgG had specificity for the pentapeptide, L-Ala-D-Glu-gamma-L-Lys-D-Ala-D-Ala, the antigenic determinant of peptidoglycan, as well as for the Fc of IgG. Detailed studies on the 7S anti-IgG from one of the antisera revealed that the pentapeptide inhibited the coprecipitation reaction of 7S anti-IgG R3387 with antigen-antibody complexes and the precipitin reaction between 7S anti-IgG R3387 and its anti-idiotype serum.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Imunoglobulina G
/
Peptidoglicano
/
Anticorpos Anti-Idiotípicos
/
Especificidade de Anticorpos
Limite:
Animals
Idioma:
En
Revista:
J Exp Med
Ano de publicação:
1973
Tipo de documento:
Article