Influence of bacterial infection on serum enzymes of white rats.
Appl Microbiol
; 17(1): 145-9, 1969 Jan.
Article
em En
| MEDLINE
| ID: mdl-4886856
ABSTRACT
Infection of white rats with Francisella tularensis (Pasteurella tularensis) and Salmonella typhimurium and exposure to the endotoxin of S. typhimurium stimulated significant increases in various serum enzymes including aldolase, lactate dehydrogenase, phosphohexose isomerase, isocitrate dehydrogenase, and glutamate-oxalacetate transaminase. The rates of changes in enzymatic activity after infection were directly related to the size of infecting dose and to the type of infective agent employed. Tularemic infection stimulated excessive changes in enzyme activity, whereas salmonellosis and endointoxication elicited less pronounced alterations of relatively short duration. Changes observed in serum enzymes after exposure to these agents reflect the severe liver damage and extensive systemic involvement noted in tularemia as opposed to more localized and less intensive tissue damage occurring during salmonellosis and endointoxication.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infecções por Pasteurella
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Aspartato Aminotransferases
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Salmonelose Animal
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Frutose-Bifosfato Aldolase
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Glucose-6-Fosfato Isomerase
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Isocitrato Desidrogenase
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L-Lactato Desidrogenase
Limite:
Animals
Idioma:
En
Revista:
Appl Microbiol
Ano de publicação:
1969
Tipo de documento:
Article