An isomorphous heavy-atom derivative of crystaline formylmethionine transfer RNA.
Science
; 177(4047): 429-31, 1972 Aug 04.
Article
em En
| MEDLINE
| ID: mdl-5043142
ABSTRACT
An isomorphous osmium derivative of crystalline yeast initiator transfer RNA has been prepared and interpreted to 6-angstrom resolution. The coordinates of the heavy atoms have been determined by Patterson and "direct" methods applied to the difference coefficients of the centric projections, followed by least-squares refinement. There is one dominant site per asymmetric unit, consistent with the finding by neutron-activation analysis that there is approximately one osmium atom per molecule of transfer RNA. The osmium derivative appears to be a normal substrate for enzymatic aminoacylation.
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Base de dados:
MEDLINE
Assunto principal:
Osmio
/
RNA de Transferência
/
Metionina
Idioma:
En
Revista:
Science
Ano de publicação:
1972
Tipo de documento:
Article