Actinomycin D: inhibition of phospholipid synthesis in chick embryo cells.
Science
; 160(3825): 316-7, 1968 Apr 19.
Article
em En
| MEDLINE
| ID: mdl-5641263
ABSTRACT
When chick embryo fibroblasts are exposed to actinomycin D for 30 minutes to 3 hours, there is progressive inhibition of phospholipid synthesis, so that by 3 hours the inhibition is 40 percent. All phospholipids are affected. Since this inhibition is twice as great as the inhibition of protein synthesis, some effects of actinomycin D previously ascribed to decreased protein synthesis must be reevaluated.
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Base de dados:
MEDLINE
Assunto principal:
Fosfolipídeos
/
Dactinomicina
/
Fibroblastos
Limite:
Animals
Idioma:
En
Revista:
Science
Ano de publicação:
1968
Tipo de documento:
Article