Precultured and fresh human T-cells suppress the mitogen response of autologous lymphocytes.
Immunol Lett
; 6(2): 97-100, 1983 Feb.
Article
em En
| MEDLINE
| ID: mdl-6221996
ABSTRACT
Human T-lymphocytes, after culture at 37 degrees C for 48 h, suppressed the Con A-induced blastogenesis of fresh autologous lymphocytes. Both Fc gamma receptor-positive and -negative T-cell subsets were active as suppressors. Non-T-cells failed to show such a phenomenon. Similarly, freshly isolated T-cells, and Fc gamma receptor-positive T-lymphocytes also suppressed the blastogenic response. Thus, preculture is not required to obtain "suppressor cells". The suppression of mitogen responses therefore seems to be an inherent property of T-cells.
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Base de dados:
MEDLINE
Assunto principal:
Ativação Linfocitária
/
Linfócitos T
/
Linfócitos T Reguladores
Limite:
Humans
Idioma:
En
Revista:
Immunol Lett
Ano de publicação:
1983
Tipo de documento:
Article