Sodium lauryl sulfate irritant patch tests. II. Variations of test responses among subjects and comparison to variations of allergic responses elicited by Toxicodendron extract.
J Am Acad Dermatol
; 11(3): 474-7, 1984 Sep.
Article
em En
| MEDLINE
| ID: mdl-6237135
ABSTRACT
Inflammation was induced on the forearms of volunteers by twenty-four closed patch tests to either the irritant 10% sodium lauryl sulfate (SLS) or Toxicodendron extract. Each chemical was tested at eight sites on the ventral forearms of each volunteer in order to assess the variability of response among test sites in individual subjects. Inflammation was assessed about 10 minutes after patch tests were removed. The degree of inflammation elicited by both Toxicodendron and SLS was variable among subjects, but variation among individual test sites was much more marked in subjects tested with SLS (p less than 0.002). The marked variability of responses to irritation that occur in any single subject may explain why irritant patch test responses do not reliably identify the irritation-prone individual.
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Base de dados:
MEDLINE
Assunto principal:
Plantas Tóxicas
/
Dodecilsulfato de Sódio
/
Extratos Vegetais
/
Toxicodendron
/
Dermatite por Toxicodendron
/
Dermatite de Contato
/
Edema
/
Eritema
Tipo de estudo:
Prognostic_studies
Limite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Am Acad Dermatol
Ano de publicação:
1984
Tipo de documento:
Article