Laryngeal papillomavirus infection during clinical remission.
N Engl J Med
; 308(21): 1261-4, 1983 May 26.
Article
em En
| MEDLINE
| ID: mdl-6302507
ABSTRACT
Biopsy samples from 20 patients with a history of laryngeal papillomas were analyzed by Southern blot hybridization for the presence of human papillomavirus DNA. All papillomas examined contained papillomavirus DNA sequences. Four samples from uninvolved sites in two patients with active disease and eight samples from patients in remission also contained viral DNA. No human papillomavirus DNA was detected in a third patient seen during remission. These results explain the clinical pattern of frequent recurrences even after long-term remission in laryngeal papillomatosis.
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Base de dados:
MEDLINE
Assunto principal:
Papiloma
/
Infecções Tumorais por Vírus
/
DNA Viral
/
Neoplasias Laríngeas
Limite:
Adolescent
/
Adult
/
Aged
/
Animals
/
Child
/
Child, preschool
/
Humans
/
Infant
/
Middle aged
Idioma:
En
Revista:
N Engl J Med
Ano de publicação:
1983
Tipo de documento:
Article