[Intrauterine malnutrition in rats. II. Study of weight and mortality of the offspring]. / Desnutrição intrauterina em ratos. II Estudo do peso e mortalidade do produto da concepção.

ABSTRACT

Rats were submitted to protein-calorie deprivation during different periods of gestation and the body weight and mortality of offspring were evaluated at 0, 28 and 90 days of age. The body weight was considered adequate (n) when the values were up to 2 SD below the mean values of control animals, or inadequate (d) when the values were below 2 SD. Rats of the control group (C) were fed ad libitum (protein 21%), and the rats of the experimental groups were fed during all gestational period (D), during the first half (D1) or second half of pregnancy (D2), with a diet containing 1% of protein, and the intake reduced to 50%. Significant differences were observed in the ponderal evolution for all experimental groups. Group D was the most damaged, with the greatest ponderal deficiency and the greatest mortality rates. Similar behavior was observed for D2. Group D1 was similar to C with the best results and the lowest mortality rate.