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Comparison of amounts of collagen and elastin in pleura and parenchyma of dog lung.
Article em En | MEDLINE | ID: mdl-6725092
Pressure-volume characteristics of the lung have been thought to be due primarily to the properties of the network of alveolar septa. However, Hajji et al. (J. Appl. Physiol.: Respirat . Environ. Exercise Physiol. 47: 175-181, 1979) attributed a substantial role to the visceral pleura. Seeking a structural explanation for this result, we compared the relative amounts of collagen fibrils and elastin fibers in the visceral pleura and alveolar parenchyma using stereological measurements in five canine lobes. We found about one-fifth as much collagen and one-tenth as much elastin in the pleura as in the alveolar parenchyma. This structural result confirms the functional conclusions of Hajji et al. We argue that such a substantial structure is not needed for protection against overinflation but may have to do with stabilization of lobe shape or handling of frictional forces.
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Base de dados: MEDLINE Assunto principal: Pleura / Colágeno / Elastina / Pulmão Limite: Animals Idioma: En Revista: J Appl Physiol Respir Environ Exerc Physiol Ano de publicação: 1984 Tipo de documento: Article
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Base de dados: MEDLINE Assunto principal: Pleura / Colágeno / Elastina / Pulmão Limite: Animals Idioma: En Revista: J Appl Physiol Respir Environ Exerc Physiol Ano de publicação: 1984 Tipo de documento: Article