Comparison of amounts of collagen and elastin in pleura and parenchyma of dog lung.
J Appl Physiol Respir Environ Exerc Physiol
; 56(5): 1383-8, 1984 May.
Article
em En
| MEDLINE
| ID: mdl-6725092
Pressure-volume characteristics of the lung have been thought to be due primarily to the properties of the network of alveolar septa. However, Hajji et al. (J. Appl. Physiol.: Respirat . Environ. Exercise Physiol. 47: 175-181, 1979) attributed a substantial role to the visceral pleura. Seeking a structural explanation for this result, we compared the relative amounts of collagen fibrils and elastin fibers in the visceral pleura and alveolar parenchyma using stereological measurements in five canine lobes. We found about one-fifth as much collagen and one-tenth as much elastin in the pleura as in the alveolar parenchyma. This structural result confirms the functional conclusions of Hajji et al. We argue that such a substantial structure is not needed for protection against overinflation but may have to do with stabilization of lobe shape or handling of frictional forces.
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Base de dados:
MEDLINE
Assunto principal:
Pleura
/
Colágeno
/
Elastina
/
Pulmão
Limite:
Animals
Idioma:
En
Revista:
J Appl Physiol Respir Environ Exerc Physiol
Ano de publicação:
1984
Tipo de documento:
Article