Anesthetics as teratogens: nitrous oxide is fetotoxic, xenon is not.
Science
; 210(4472): 899-901, 1980 Nov 21.
Article
em En
| MEDLINE
| ID: mdl-7434002
ABSTRACT
Exposure of pregnant rats to the anesthetic nitrous oxide on the ninth day of gestation causes fetal resorption, skeletal anomalies, and macroscopic lesions including encephalocele, anophthalmia, microphthalmia, and gastroschisis. The inert gas xenon, which has anesthetic properties similar to those of nitrous oxide, does not cause teratogenic effects under the same experimental conditions.
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Base de dados:
MEDLINE
Assunto principal:
Teratogênicos
/
Xenônio
/
Anestésicos
/
Óxido Nitroso
Limite:
Animals
/
Pregnancy
Idioma:
En
Revista:
Science
Ano de publicação:
1980
Tipo de documento:
Article