[Pterygium excision with intra-operative administration of low dosage mitomycin C]. / Pterygiumexzision mit intraoperativer Applikation von niedrig dosiertem Mitomycin C.
Ophthalmologe
; 92(4): 458-62, 1995 Aug.
Article
em De
| MEDLINE
| ID: mdl-7549329
ABSTRACT
Pterygium excision with postoperative instillation of mitoymcin C (MMC, 0.4 mg/ml) is encouraging because of the technical simplicity and low recurrence rates, but serious postoperative complications have been described (scleral necrosis, corneal perforation, glaucoma, cataract). The authors studied the efficacy and safety of pterygium excisions with a single intraoperative application of low-dose MMC (0.2 mg/ml). Pterygium excision (bare sclera technique) was performed in 18 patients with primary or recurrent pterygia. MMC (0.2 mg/ml) was applied intraoperatively (5 min) to the exposed sclera. Patients were followed up for signs of recurrence and complications. There were four recurrences (mean follow-up 13.8 months). Postoperative complications consisted of granuloma formation (n = 2). Delayed conjunctival healing was observed in all cases. Scleral necrosis, corneal complications, cataract, or glaucoma were not seen. Intraoperative application of MMC apparently reduces the recurrence rate after pterygium excision. The use of a 0.2 mg/ml concentration of MMC appears to be safe.
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Base de dados:
MEDLINE
Assunto principal:
Pterígio
/
Mitomicina
/
Antibióticos Antineoplásicos
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
De
Revista:
Ophthalmologe
Assunto da revista:
OFTALMOLOGIA
Ano de publicação:
1995
Tipo de documento:
Article