Bullous pemphigoid successfully controlled by tetracycline and nicotinamide.
Br J Dermatol
; 133(1): 88-90, 1995 Jul.
Article
em En
| MEDLINE
| ID: mdl-7669647
ABSTRACT
In 1986, Berk and Lorincz reported the efficacy of tetracycline and nicotinamide in the treatment of bullous pemphigoid (BP). In the present study of seven patients with BP, we found that a regimen of 2 g tetracycline combined with 2 g nicotinamide daily was effective in clearing the skin lesions. Total remission was achieved within 6-8 weeks, after which the dose was gradually tapered. The mean duration of therapy was 7 months. No effect on the titre of antibasement membrane antibodies was observed. The mode of action of this therapy is unknown.
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Base de dados:
MEDLINE
Assunto principal:
Tetraciclina
/
Penfigoide Bolhoso
/
Niacinamida
/
Antibacterianos
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Br J Dermatol
Ano de publicação:
1995
Tipo de documento:
Article
País de afiliação:
Holanda