In vivo reactions of Ca,P particle containing surface reactive glasses.
J Biomed Mater Res
; 28(9): 993-1002, 1994 Sep.
Article
em En
| MEDLINE
| ID: mdl-7814440
ABSTRACT
Four Ca,P particle containing surface reactive glass composites and two glasses (in the SiO2-CaO-P2O5-Na2O-Al2O3-B2O3 system) were implanted in the diaphyseal area of goat femora up to 24 weeks. Scanning electron microscopic, energy dispersive x-ray, and histological analysis were performed to evaluate the material-tissue interactions. A new type of integration mechanism was observed. Instead of the bone growing to the material surface, a gel-like silica formation appeared between the cortex bone and the material surface. In time the gel-like formation was replaced by a Ca,P layer. The results provided indirect evidence that pure silica gel formed in the tissues could also achieve an apatite layer formation and bone bonding on its surface.
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Base de dados:
MEDLINE
Assunto principal:
Fósforo
/
Materiais Biocompatíveis
/
Cálcio
/
Vidro
Limite:
Animals
Idioma:
En
Revista:
J Biomed Mater Res
Ano de publicação:
1994
Tipo de documento:
Article
País de afiliação:
Finlândia