Intestinal microsporidiosis with Septata intestinalis in a patient with AIDS--response to albendazole.
J Infect
; 31(3): 237-9, 1995 Nov.
Article
em En
| MEDLINE
| ID: mdl-8586846
ABSTRACT
Microsporidiosis is a common finding in HIV-infected patients who have diarrhoea. The species most commonly causing gastrointestinal disease is Enterocytozoon bieneusi. Recently Septata intestinalis has been described as a cause of diarrhoea and disseminated infection in patients with AIDS. A 44-year-old homosexual man with severe immunodeficiency (CD4 cell count 40/microliters) had a history of watery diarrhoea for 2 weeks. Microsporidian spores measuring 1.2 to 1.5 x 2.5 to 3.0 microns were found in stool samples. Electron microscopy of duodenal biopsies confirmed the diagnosis of intestinal microsporidiosis and showed parasitophorous vacuoles with the typical ultrastructure of S. intestinalis. The patient was treated with albendazole (400 mg twice daily) and became asymptomatic within 4 days. No spores could be detected in stool samples after a treatment period of 14 days. About 25 infections with S. intestinalis have been reported to date, and the case presented here is the first in a German patient.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Albendazol
/
Síndrome da Imunodeficiência Adquirida
/
Microsporidiose
/
Microsporídios
/
Infecções Oportunistas Relacionadas com a AIDS
/
Diarreia
/
Anti-Helmínticos
Limite:
Adult
/
Animals
/
Humans
/
Male
Idioma:
En
Revista:
J Infect
Ano de publicação:
1995
Tipo de documento:
Article
País de afiliação:
Alemanha