Studies on sodium ion retention and antidiuretic effects after administration of L-tryptophan to rats.
Naunyn Schmiedebergs Arch Pharmacol
; 297(3): 213-7, 1977 Apr.
Article
em En
| MEDLINE
| ID: mdl-876398
ABSTRACT
Under certain conditions the i.p. injection of L-tryptophan leads to a reduction of elimination of Na+. At the same time, the fractional Na+ -reabsorption increases. No increase in the absolute tubular sodium transport rate was observed since the significantly reduced plasma-sodium concentration leads to a decreased sodium load. The most probable cause of a decreased plasma-sodium concentration seems to be a retention of sodium-free water under the chosen conditions of infusion. The water retention is compatible with the antidiuretic effect of 5-hydroxytryptamine.
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Base de dados:
MEDLINE
Assunto principal:
Sódio
/
Triptofano
/
Diurese
Limite:
Animals
Idioma:
En
Revista:
Naunyn Schmiedebergs Arch Pharmacol
Ano de publicação:
1977
Tipo de documento:
Article