Widespread cutaneous necrosis associated with antiphospholipid syndrome.
Clin Rheumatol
; 15(4): 394-8, 1996 Jul.
Article
em En
| MEDLINE
| ID: mdl-8853176
ABSTRACT
Widespread cutaneous necrosis as the catastrophic manifestation in antiphospholipid syndrome (APLS) is rather uncommon. Even in the few documented cases, the extensive skin necrosis lesions have been stabilized and regressed with eventual healing utilizing pulse steroid therapy alone or in conjunction with further treatment with plasmapheresis. We describe one case of APLS associated with lupus-like disease. The young female suffered from widespread cutaneous necrosis of the lower legs and gangrene change in the digital end of hands and feet. This condition necessitated amputation of major lower extremities and digital amputation of both hands.
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Base de dados:
MEDLINE
Assunto principal:
Dermatopatias
/
Síndrome Antifosfolipídica
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Clin Rheumatol
Ano de publicação:
1996
Tipo de documento:
Article