A racial difference in the prevalence of the Arg506-->Gln mutation.
Thromb Res
; 81(5): 577-81, 1996 Mar 01.
Article
em En
| MEDLINE
| ID: mdl-8907316
ABSTRACT
Several recent studies have reported that the factor V Arg506-->Gln mutation is present in 3-10% of adults of European descent. To determine if the prevalence is comparable among Blacks, we have initiated a case-control study in a large urban hospital in Atlanta which serves a substantial black population. We have evaluated 131 black subjects with confirmed venous or arterial thrombosis and 61 black subjects without a history of thrombosis. Only one case and one control were positive for the Arg506-->Gln mutation. We conclude that the mutation is more common among Whites than Blacks.
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Base de dados:
MEDLINE
Assunto principal:
Arginina
/
Fator V
/
Mutação Puntual
/
Glicina
Tipo de estudo:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Thromb Res
Ano de publicação:
1996
Tipo de documento:
Article
País de afiliação:
Estados Unidos