Integrins and cancer.
Curr Opin Cell Biol
; 8(5): 724-30, 1996 Oct.
Article
em En
| MEDLINE
| ID: mdl-8939661
ABSTRACT
The past year or two has seen great advances in the elucidation of significant roles for integrins in cancer cells. These include roles in signal transduction, gene expression, proliferation, apoptosis regulation, invasion and metastasis, and angiogenesis. In particular, integrin alphavbeta3 has been implicated in the neovascularization of tumors. In addition, this integrin has been shown to contribute to the survival, proliferation and metastatic phenotype of human melanoma.
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Base de dados:
MEDLINE
Assunto principal:
Transdução de Sinais
/
Integrinas
/
Neoplasias
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Curr Opin Cell Biol
Ano de publicação:
1996
Tipo de documento:
Article
País de afiliação:
Estados Unidos