Analysis of ribosomal and alphoid repetitive DNA by fiber-FISH.

Shiels, C; Coutelle, C; Huxley, C

Shiels, C; Coutelle, C; Huxley, C.

Afiliação

Shiels C; Department of Biochemistry and Molecular Genetics, Imperial College School of Medicine at St. Mary's London, UK.

Cytogenet Cell Genet ; 76(1-2): 20-2, 1997.

Article em En | MEDLINE | ID: mdl-9154117

ABSTRACT

ABSTRACT

We have used fluorescence in situ hybridization to extended DNA fibers (fiber-FISH) to analyse the alpha-satellite and rDNA arrays on a human chromosome 22. The rDNA could be seen as a string of signals spanning about 430 kb. The bulk of the alphoid DNA was found in a single large array of about 2.6 Mb.

Assuntos

Cromossomos Humanos Par 22; DNA Ribossômico; Hibridização in Situ Fluorescente; Sequências Repetitivas de Ácido Nucleico; Linhagem Celular; Humanos; Ribossomos

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Base de dados: MEDLINE Assunto principal: Cromossomos Humanos Par 22 / DNA Ribossômico / Sequências Repetitivas de Ácido Nucleico / Hibridização in Situ Fluorescente Limite: Humans Idioma: En Revista: Cytogenet Cell Genet Ano de publicação: 1997 Tipo de documento: Article País de afiliação: Reino Unido

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