A bacterial RNA that functions as both a tRNA and an mRNA.
Trends Biochem Sci
; 23(1): 25-9, 1998 Jan.
Article
em En
| MEDLINE
| ID: mdl-9478132
ABSTRACT
Bacterial tmRNA (transfer-messenger RNA, also known as 10Sa RNA) contains a tRNA-like structure in the 5'- and 3'-end sequences and an internal reading frame encoding a 'tag' peptide. The dual function of this molecule as both a tRNA and an mRNA facilitates a trans-translation reaction, in which a ribosome can switch between translation of a truncated mRNA and the tmRNA's tag sequence. The result is a chimeric protein with the tag peptide attached to the C-terminus of the truncated peptide.
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Base de dados:
MEDLINE
Assunto principal:
RNA Bacteriano
/
RNA Mensageiro
/
RNA de Transferência
Idioma:
En
Revista:
Trends Biochem Sci
Ano de publicação:
1998
Tipo de documento:
Article
País de afiliação:
Japão