Leukocyte chemotaxis in diabetic patients and their nondiabetic first-degree relatives.
Diabetes
; 25(2 SUPPL): 880-3, 1976.
Article
em En
| MEDLINE
| ID: mdl-971792
ABSTRACT
Leukocyte chemotaxis wasmeasured in 108 subjects:
20 normal controls, 36 insulin-taking diabetics (15 being index patients), and 52 nondiabetic first-degree relatives of index patients. The relatives had a mean chemotactic index (CI) significantly lower than that of the controls (individually, 25 per cent had CIs lower than the lowest of the controls); and the diabetics had a mean CI significantly lower than that of the relatives. The impairment of leukocyte chemotaxis measured in the first-degree relatives of diabetic index patients does not appear to be associated with an increased susceptibility to infection and suggests that the impaired leukotaxis is due to an inherent defect--perhaps genetic--in leukocyte function.
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Base de dados:
MEDLINE
Assunto principal:
Diabetes Mellitus
Limite:
Adolescent
/
Adult
/
Aged
/
Child
/
Humans
/
Middle aged
Idioma:
En
Revista:
Diabetes
Ano de publicação:
1976
Tipo de documento:
Article