Systemic lupus erythematosus associated with acute Epstein-Barr virus infection.
Am J Kidney Dis
; 32(5): 825-8, 1998 Nov.
Article
em En
| MEDLINE
| ID: mdl-9820454
ABSTRACT
Systemic lupus erythematosus (SLE) is a multisystem disease of unknown origin, characterized by a variety of autoimmune phenomena. Viruses have long been postulated to play a role in its pathogenesis. Several observations suggested a link between Epstein-Barr virus (EBV) and SLE. We describe a 14-year-old girl who presented with acute onset of SLE concurrently with clinical and laboratory findings consistent with EBV-induced infectious mononucleosis (IM). Evidence for acute EBV infection was confirmed by serological studies and detection of specific EBV antigens on kidney biopsy. This close association between EBV and SLE suggests a possible role of the virus in the pathogenesis of SLE in this patient.
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Base de dados:
MEDLINE
Assunto principal:
Infecções por Vírus Epstein-Barr
/
Lúpus Eritematoso Sistêmico
Tipo de estudo:
Diagnostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Female
/
Humans
Idioma:
En
Revista:
Am J Kidney Dis
Ano de publicação:
1998
Tipo de documento:
Article
País de afiliação:
Israel