Calcinogenic factor in Solanum malacoxylon: evidence that it is 1,25-dihydroxyvitamin D3-glycoside.
Science
; 194(4267): 853-5, 1976 Nov 19.
Article
em En
| MEDLINE
| ID: mdl-982048
ABSTRACT
After glycosidic cleavage of the water-soluble vitamin D-like principle of the calcinogenic plant Solanum malacoxylon, the active lipophilic portion was purified by column chromatography and analyzed by combined gas chromatography and mass spectrometry. It was identified as 1,25-dihydroxyvitamin D3, the active form of vitamin D. Thus this active metabolite of vitamin D exists in the plant world, and its presence probably accounts for pathologic calcification in grazing animals ingesting Solanum malacoxylon.
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Base de dados:
MEDLINE
Assunto principal:
Plantas Tóxicas
/
Calcinose
/
Di-Hidroxicolecalciferóis
/
Hidroxicolecalciferóis
Tipo de estudo:
Prognostic_studies
Idioma:
En
Revista:
Science
Ano de publicação:
1976
Tipo de documento:
Article