Nephrotic syndrome and human parvovirus infection in homozygous sickle-cell disease: a temporal association - abstract
West Indian med. j
; 44(Suppl. 2): 27, Apr. 1995.
Article
em En
| MedCarib
| ID: med-5776
Biblioteca responsável:
JM3.1
Localização: JM3.1; R18.W4
ABSTRACT
Proteinuria of sufficient severity to manifest the nephrotic syndrome and renal impairment has been associated with human parvovirus (B19) infection in 7 patients with homozygous sickle-cell (SS) disease. In most patients, the proteinuria resolved but renal impairment remained. The glomerular histology showed evidence of segmental proliferative glomerulonephritis in 4 out of 5 biopsies. Most events occurred within 2 weeks of B19 associated aplastic crisis, and the mechanism is at present unknown. This association may add to the pathogenic significance of B19 infection in SS disease (AU)
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Base de dados:
MedCarib
Assunto principal:
Infecções por Parvoviridae
/
Anemia Falciforme
/
Síndrome Nefrótica
Tipo de estudo:
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
West Indian med. j
Ano de publicação:
1995
Tipo de documento:
Article
/
Congress and conference