Detalhe da pesquisa
1.
Predicting Optimal Antimalarial Drug Combinations from a Standardized Plasmodium falciparum Humanized Mouse Model.
Antimicrob Agents Chemother
; 67(6): e0157422, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37133382
2.
Anti-malarial ozonides OZ439 and OZ609 tested at clinically relevant compound exposure parameters in a novel ring-stage survival assay.
Malar J
; 18(1): 427, 2019 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31849323
3.
A Randomized Trial Evaluating the Prophylactic Activity of DSM265 Against Preerythrocytic Plasmodium falciparum Infection During Controlled Human Malarial Infection by Mosquito Bites and Direct Venous Inoculation.
J Infect Dis
; 217(5): 693-702, 2018 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29216395
4.
Surface attachment, promoted by the actomyosin system of Toxoplasma gondii is important for efficient gliding motility and invasion.
BMC Biol
; 15(1): 1, 2017 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28100223
5.
UAP56 is a conserved crucial component of a divergent mRNA export pathway in Toxoplasma gondii.
Mol Microbiol
; 102(4): 672-689, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27542978
6.
Multiplex, DNase-free one-step reverse transcription PCR for Plasmodium 18S rRNA and spliced gametocyte-specific mRNAs.
Malar J
; 16(1): 208, 2017 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28526032
7.
Conditional genome engineering in Toxoplasma gondii uncovers alternative invasion mechanisms.
Nat Methods
; 10(2): 125-7, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23263690
8.
AMA1-deficient Toxoplasma gondii parasites transiently colonize mice and trigger an innate immune response that leads to long-lasting protective immunity.
Infect Immun
; 83(6): 2475-86, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25847964
9.
Robust inducible Cre recombinase activity in the human malaria parasite Plasmodium falciparum enables efficient gene deletion within a single asexual erythrocytic growth cycle.
Mol Microbiol
; 88(4): 687-701, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23489321
10.
A pharmacokinetic-pharmacodynamic model for chemoprotective agents against malaria.
CPT Pharmacometrics Syst Pharmacol
; 12(1): 50-61, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36412499
11.
Host cell invasion by apicomplexan parasites: the junction conundrum.
PLoS Pathog
; 10(9): e1004273, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25232721
12.
Improved safety margin for embryotoxicity in rats for the new endoperoxide artefenomel (OZ439) as compared to artesunate.
Birth Defects Res
; 110(7): 553-578, 2018 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29193867
13.
Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study.
Lancet Infect Dis
; 18(8): 874-883, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29909069
14.
The toxoplasma Acto-MyoA motor complex is important but not essential for gliding motility and host cell invasion.
PLoS One
; 9(3): e91819, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24632839
15.
Calcium-dependent phosphorylation alters class XIVa myosin function in the protozoan parasite Toxoplasma gondii.
Mol Biol Cell
; 25(17): 2579-91, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24989796
16.
Apical membrane antigen 1 mediates apicomplexan parasite attachment but is dispensable for host cell invasion.
Nat Commun
; 4: 2552, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24108241