Detalhe da pesquisa
1.
The Herpes Simplex Virus pUL16 and pUL21 Proteins Prevent Capsids from Docking at Nuclear Pore Complexes.
PLoS Pathog
; 19(12): e1011832, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38039340
2.
Dynamin-related protein 1 is a critical regulator of mitochondrial calcium homeostasis during myocardial ischemia/reperfusion injury.
FASEB J
; 38(1): e23379, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38133921
3.
Macrophage-NLRP3 Activation Promotes Right Ventricle Failure in Pulmonary Arterial Hypertension.
Am J Respir Crit Care Med
; 206(5): 608-624, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35699679
4.
PINK1-induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension.
FASEB J
; 35(8): e21771, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34275172
5.
Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis.
Circ Res
; 126(12): 1723-1745, 2020 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32216531
6.
The molecular mechanisms of oxygen-sensing in human ductus arteriosus smooth muscle cells: A comprehensive transcriptome profile reveals a central role for mitochondria.
Genomics
; 113(5): 3128-3140, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34245829
7.
Identification of Long Noncoding RNA H19 as a New Biomarker and Therapeutic Target in Right Ventricular Failure in Pulmonary Arterial Hypertension.
Circulation
; 142(15): 1464-1484, 2020 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32698630
8.
Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension.
Circulation
; 141(24): 1986-2000, 2020 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32192357
9.
An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications.
FASEB J
; 34(4): 5106-5127, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32068312
10.
Identification of novel dynamin-related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia-reperfusion injury.
FASEB J
; 34(1): 1447-1464, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31914641
11.
Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction.
Circ Res
; 124(12): 1727-1746, 2019 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30922174
12.
Metabolic Syndrome Exacerbates Pulmonary Hypertension due to Left Heart Disease.
Circ Res
; 125(4): 449-466, 2019 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31154939
13.
Endothelial BMPR2 Loss Drives a Proliferative Response to BMP (Bone Morphogenetic Protein) 9 via Prolonged Canonical Signaling.
Arterioscler Thromb Vasc Biol
; 40(11): 2605-2618, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32998516
14.
Clinical value of non-coding RNAs in cardiovascular, pulmonary, and muscle diseases.
Am J Physiol Cell Physiol
; 318(1): C1-C28, 2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31483703
15.
Suppression of Superoxide-Hydrogen Peroxide Production at Site IQ of Mitochondrial Complex I Attenuates Myocardial Stunning and Improves Postcardiac Arrest Outcomes.
Crit Care Med
; 48(2): e133-e140, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31939812
16.
Standards and Methodological Rigor in Pulmonary Arterial Hypertension Preclinical and Translational Research.
Circ Res
; 122(7): 1021-1032, 2018 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29599278
17.
Excess Protein O-GlcNAcylation Links Metabolic Derangements to Right Ventricular Dysfunction in Pulmonary Arterial Hypertension.
Int J Mol Sci
; 21(19)2020 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33019763
18.
Providing care for the 99.9% during the COVID-19 pandemic: How ethics, equity, epidemiology, and cost per QALY inform healthcare policy.
Healthc Manage Forum
; 33(5): 239-242, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32638633
19.
Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic and Therapeutic Implications.
Circulation
; 138(3): 287-304, 2018 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29431643
20.
Assessment of Right Ventricular Function in the Research Setting: Knowledge Gaps and Pathways Forward. An Official American Thoracic Society Research Statement.
Am J Respir Crit Care Med
; 198(4): e15-e43, 2018 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30109950