Detalhe da pesquisa
1.
Validating Small Molecule Chemical Probes for Biological Discovery.
Annu Rev Biochem
; 91: 61-87, 2022 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35363509
2.
HMCES Functions in the Alternative End-Joining Pathway of the DNA DSB Repair during Class Switch Recombination in B Cells.
Mol Cell
; 77(2): 384-394.e4, 2020 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31806351
3.
Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell
; 149(1): 214-31, 2012 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-22464331
4.
ChemRAP uncovers specific mRNA translation regulation via RNA 5' phospho-methylation.
EMBO Rep
; 25(3): 1570-1588, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38263329
5.
SETD7 functions as a transcription repressor in prostate cancer via methylating FOXA1.
Proc Natl Acad Sci U S A
; 120(33): e2220472120, 2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37549269
6.
The SMX DNA Repair Tri-nuclease.
Mol Cell
; 65(5): 848-860.e11, 2017 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28257701
7.
Dissecting the stability determinants of a challenging de novo protein fold using massively parallel design and experimentation.
Proc Natl Acad Sci U S A
; 119(41): e2122676119, 2022 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36191185
8.
The RavA-ViaA chaperone complex modulates bacterial persistence through its association with the fumarate reductase enzyme.
J Biol Chem
; 299(10): 105199, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37660904
9.
Structure and activity of human TMPRSS2 protease implicated in SARS-CoV-2 activation.
Nat Chem Biol
; 18(9): 963-971, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35676539
10.
PRMT inhibition induces a viral mimicry response in triple-negative breast cancer.
Nat Chem Biol
; 18(8): 821-830, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35578032
11.
A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization.
Nat Chem Biol
; 18(1): 56-63, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34782742
12.
Detection of antibodies against the huntingtin protein in human plasma.
Cell Mol Life Sci
; 80(2): 45, 2023 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36651994
13.
The MYC oncoprotein directly interacts with its chromatin cofactor PNUTS to recruit PP1 phosphatase.
Nucleic Acids Res
; 50(6): 3505-3522, 2022 04 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35244724
14.
Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer.
Genes Dev
; 30(7): 772-85, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26988419
15.
Discovery of a Potent and Selective Targeted NSD2 Degrader for the Reduction of H3K36me2.
J Am Chem Soc
; 145(14): 8176-8188, 2023 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36976643
16.
Discovery of a Novel DCAF1 Ligand Using a Drug-Target Interaction Prediction Model: Generalizing Machine Learning to New Drug Targets.
J Chem Inf Model
; 63(13): 4070-4078, 2023 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37350740
17.
Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy.
Nature
; 549(7671): 227-232, 2017 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28854171
18.
Cbx2 targets PRC1 to constitutive heterochromatin in mouse zygotes in a parent-of-origin-dependent manner.
Mol Cell
; 58(1): 157-71, 2015 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25801166
19.
HMCES Functions in the Alternative End-Joining Pathway of the DNA DSB Repair during Class Switch Recombination in B Cells.
Mol Cell
; 77(5): 1154, 2020 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32142687
20.
The human pseudouridine synthase PUS7 recognizes RNA with an extended multi-domain binding surface.
Nucleic Acids Res
; 49(20): 11810-11822, 2021 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34718722