Detalhe da pesquisa
1.
A novel JAK-STAT inhibitor, 2-[(3-Carbamoyl-2-thienyl)amino]-2-oxoethyl(2,6-dichlorophenyl)acetate, suppresses helper T cell differentiation in vitro and collagen-induced arthritis in vivo.
Biochem Biophys Res Commun
; 468(4): 766-73, 2015 Dec 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26562526
2.
CDK inhibitors suppress Th17 and promote iTreg differentiation, and ameliorate experimental autoimmune encephalomyelitis in mice.
Biochem Biophys Res Commun
; 435(3): 378-84, 2013 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23665028
3.
Pyridone 6, a pan-JAK inhibitor, ameliorates allergic skin inflammation of NC/Nga mice via suppression of Th2 and enhancement of Th17.
J Immunol
; 187(9): 4611-20, 2011 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21957150
4.
Smad2 and Smad3 are redundantly essential for the TGF-beta-mediated regulation of regulatory T plasticity and Th1 development.
J Immunol
; 185(2): 842-55, 2010 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20548029
5.
SOCS1 is essential for regulatory T cell functions by preventing loss of Foxp3 expression as well as IFN-{gamma} and IL-17A production.
J Exp Med
; 208(10): 2055-67, 2011 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21893603
6.
Tyrosine kinase inhibitor, methyl 2,5-dihydromethylcinnimate, induces PML nuclear body formation and apoptosis in tumor cells.
Exp Cell Res
; 313(13): 2753-65, 2007 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17585903