Detalhe da pesquisa
1.
KCNE1 is an auxiliary subunit of two distinct ion channel superfamilies.
Cell
; 184(2): 534-544.e11, 2021 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33373586
2.
Allosteric inhibitors targeting the calmodulin-PIP2 interface of SK4 K+ channels for atrial fibrillation treatment.
Proc Natl Acad Sci U S A
; 119(34): e2202926119, 2022 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35969786
3.
M-Current Inhibition in Hippocampal Excitatory Neurons Triggers Intrinsic and Synaptic Homeostatic Responses at Different Temporal Scales.
J Neurosci
; 40(19): 3694-3706, 2020 05 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32277041
4.
M-current inhibition rapidly induces a unique CK2-dependent plasticity of the axon initial segment.
Proc Natl Acad Sci U S A
; 114(47): E10234-E10243, 2017 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29109270
5.
Competition of calcified calmodulin N lobe and PIP2 to an LQT mutation site in Kv7.1 channel.
Proc Natl Acad Sci U S A
; 114(5): E869-E878, 2017 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28096388
6.
Structural Insights into the M-Channel Proximal C-Terminus/Calmodulin Complex.
Biochemistry
; 55(38): 5353-65, 2016 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27564677
7.
Long QT mutations at the interface between KCNQ1 helix C and KCNE1 disrupt I(KS) regulation by PKA and PIP2.
J Cell Sci
; 127(Pt 18): 3943-55, 2014 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25037568
8.
Maturation- and sex-sensitive depression of hippocampal excitatory transmission in a rat schizophrenia model.
Brain Behav Immun
; 51: 240-251, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26327125
9.
Mechanisms underlying the cardiac pacemaker: the role of SK4 calcium-activated potassium channels.
Acta Pharmacol Sin
; 37(1): 82-97, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26725737
10.
SK4 Ca2+ activated K+ channel is a critical player in cardiac pacemaker derived from human embryonic stem cells.
Proc Natl Acad Sci U S A
; 110(18): E1685-94, 2013 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23589888
11.
Promiscuous gating modifiers target the voltage sensor of K(v)7.2, TRPV1, and H(v)1 cation channels.
FASEB J
; 28(6): 2591-602, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24599966
12.
The SK4 channel allosteric blocker, BA6b9, reduces atrial fibrillation substrate in rats with reduced ejection fraction.
PNAS Nexus
; 3(5): pgae192, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38783894
13.
KCNQ1 channels do not undergo concerted but sequential gating transitions in both the absence and the presence of KCNE1 protein.
J Biol Chem
; 287(41): 34212-24, 2012 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-22908235
14.
Multifaceted modulation of K+ channels by protein-tyrosine phosphatase ε tunes neuronal excitability.
J Biol Chem
; 287(33): 27614-28, 2012 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22722941
15.
Intracellular domains interactions and gated motions of I(KS) potassium channel subunits.
EMBO J
; 28(14): 1994-2005, 2009 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-19521339
16.
Targeting the voltage sensor of Kv7.2 voltage-gated K+ channels with a new gating-modifier.
Proc Natl Acad Sci U S A
; 107(35): 15637-42, 2010 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-20713704
17.
Contextual fear response is modulated by M-type K+ channels and is associated with subtle structural changes of the axon initial segment in hippocampal GABAergic neurons.
AIMS Neurosci
; 10(1): 33-51, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37077956
18.
The Concise Guide to PHARMACOLOGY 2023/24: Ion channels.
Br J Pharmacol
; 180 Suppl 2: S145-S222, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38123150
19.
Excitatory and inhibitory hippocampal neurons differ in their homeostatic adaptation to chronic M-channel modulation.
Front Mol Neurosci
; 15: 972023, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36311018
20.
CKII Control of Axonal Plasticity Is Mediated by Mitochondrial Ca2+ via Mitochondrial NCLX.
Cells
; 11(24)2022 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36552754