Detalhe da pesquisa
1.
Histone deacetylase inhibitors with a primary amide zinc binding group display antitumor activity in xenograft model.
Bioorg Med Chem Lett
; 19(11): 3081-4, 2009 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19410459
2.
Synthesis and evaluation of novel phosphoramidate prodrugs of 2'-methyl cytidine as inhibitors of hepatitis C virus NS5B polymerase.
Bioorg Med Chem Lett
; 19(5): 1392-5, 2009 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19181520
3.
Optimization of a series of potent and selective ketone histone deacetylase inhibitors.
Bioorg Med Chem Lett
; 18(20): 5528-32, 2008 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18809328
4.
2-(2-Thienyl)-5,6-dihydroxy-4-carboxypyrimidines as inhibitors of the hepatitis C virus NS5B polymerase: discovery, SAR, modeling, and mutagenesis.
J Med Chem
; 49(5): 1693-705, 2006 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-16509585
5.
Enhancement of intestinal absorption of 2-methyl cytidine prodrugs.
Drug Deliv
; 17(4): 214-22, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20233089
6.
Phosphoramidate prodrugs of 2'-C-methylcytidine for therapy of hepatitis C virus infection.
J Med Chem
; 52(17): 5394-407, 2009 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19725579
7.
Optimization of thienopyrrole-based finger-loop inhibitors of the hepatitis C virus NS5B polymerase.
ChemMedChem
; 4(10): 1695-713, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19672916
8.
Identification and biological evaluation of a series of 1H-benzo[de]isoquinoline-1,3(2H)-diones as hepatitis C virus NS5B polymerase inhibitors.
J Med Chem
; 52(16): 5217-27, 2009 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19877603
9.
Identification of thieno[3,2-b]pyrroles as allosteric inhibitors of hepatitis C virus NS5B polymerase.
Bioorg Med Chem Lett
; 16(15): 4026-30, 2006 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16714108